news

May 14, 2025 Pleased to share our recent contribution to a compendium on Interorgan Crosstalk in Heart Failure and Cardiometabolic Disease, now published in Circulation Research. We teamed up with clinical trialists and multidisciplinary experts to examine the evolving landscape of interorgan communication in heart failure, with a focus on the cardio-kidney-liver-metabolic axis. This topic is particularly relevant to us in Singapore, where cardiovascular and metabolic diseases are highly prevalent and intersecting in complex ways. Grateful to our collaborators and the editors for the opportunity to be part of this important effort ! 🔗 Read our article: https://lnkd.in/gCzPjQ92 📚 Full compendium: https://lnkd.in/geujrqWt
May 14, 2025 Pleased to share our collaborative research, now published in Nature Cardiovascular Research led by Nilanjana Sadhu and the folks at Nanyang Technological University Singapore. Using safe-harbor hESCs, we leveraged on robust genetic and metabolic evidence from Asian cohorts to engineer overexpression and loss-of-function hESC stable cell lines, validating the causality of FDX1 and 3BH5C. Read it here: https://www.nature.com/articles/s44161-025-00638-w PMID: 40360795
May 14, 2025 Speaking at the International Society for Heart Research (ISHR) World Congress ! and Hosting the ECI Symposium and Panel discussions. Fellow ECIs fall in ! For more details: https://www.ishr2025nara.jp/
Jul 05, 2024 Published Editorial on the role of TRIM35 in p53-induced Heart Failure Pathogenesis in Circ Research. DOI: 10.1161/CIRCRESAHA.124.324792 PMID: 38963873
May 17, 2024 Our Manuscript on adherens junction and hippo-yap signaling regulation on cardiomyocyte differentiation is now published in Circulation! doi: 10.1161/CIRCULATIONAHA.122.061335 PMID: 38752370
Apr 17, 2024 Short Talk at the Cardiovascular epigenetics and Gene Regulation KEYSTONE SYMPOSIA 2024
Dec 01, 2023 Invited to Speak on Stem Cell quality control and CRISPR gene-editing at the 15TH STEM CELL SOCIETY SINGAPORE SYMPOSIUM 2023 “STEM CELL INNOVATIONS IN RESEARCH AND HEALTHCARE”
Nov 01, 2023 Attended and Presented on the work on NF2 at the 9th International Conference on Hippo Signalling in Development, Disease and New Therapies
Jul 20, 2023 Abstract Winner at the Epigenetics Gordon Research Conference and Seminar (Ventura, California) Abstract 1: Validating functional histone-acetylated variant enhancers in human hearts using a STARR-seq approach Abstract 2: Genome-Wide CRISPR Screen identifies NF2-adheren junction mechanistic dependency for cardiac lineage
Jul 14, 2023 Attended the International Society for Stem Cell Research (ISSCR 2023) Conference (Boston, MA) !
Dec 15, 2022 National Cardiovascular Research Symposium – Oral Presentation (Abstract Winner) !
Nov 08, 2022 14th Stem Cell Society Singapore Symposium – Outstanding Poster Award on our work on CRISPR screening for regulators of cardiac lineage specification
Sep 20, 2022 Thrilled to have defended my PhD Thesis!!
Oct 15, 2021 Nominated Best poster submission at the SingHealth Duke-NUS Scientific Congress
Aug 07, 2019 Announcement_2
Jan 14, 2018 Awarded the Kwan Im Thong Hood Cho PhD Graduate Research Scholarship!